We are thrilled to inform you about the science of eye tracking. Every month, we will keep you updated on the latest news shared by the scientific community. The newsletter of this month is related to the analysis of eye movements for the early diagnosis, differential diagnosis and follow-up of Parkinson’s disease.
We are also excited to announce you that a first prototype of NeuroClues TM is ready! NeuroClues * is a portable lab that will help you instantaneously measure your clinical exam . Do not hesitate to contact us for a demo.
The P3Lab team
*The product is not yet available for sale and will soon undergo clinical investigations.
There is a wealth of scientific knowledge about eye movements analysis for the early diagnosis, differential diagnosis and follow-up of Parkinson’s Disease. We list here one of many examples for each field of application:
Recent studies have identified antisaccades latency as a predictive biomarker to identify the subpopulation of Parkinson patients who will develop freezing of gait, up till 5 years in advance!
Expected variations of oculomotor biomarkers for pathological populations with movement disorders can help differentiate Parkinson’s disease from another movement disorder disease.
Legends: PD: Idiopathic Parkinson’s Disease ; MSA: Multiple System Atrophy ; CBS: Corticobasal Syndrome; PSP: Progressive Supranuclear Palsy ; LBD: Lewy body Dementia; PDD: Parkinson’s Disease Dementia; ATD: Alzheimer’s type Dementia; PNFA: Progressive Nonfluent Aphasia; FTD/tau: Frontotemporal Dementia – tauopathies ; FTD/TDP: Frontotemporal Dementia: – Proteinopathies; sw : square waves ; dbn : downbeat nystagmus ; e.s. : express saccade
Adapted from Leigh, R. &. (2015-06). The Neurology of Eye Movements. Oxford, UK: Oxford University Press.
A recent meta-analysis confirms that antisaccade latency and error rate are significantly increased in PD. Furthermore acute administration of levodopa had no significant effects on antisaccade performance in a small number of eligible studies.