Today, this wealth of scientific knowledge can be used in consultation to help the practitioners quantify their clinical examination. We list here one of many examples for each field of application:
Recent studies have identified antisaccades latency as a predictive biomarker to identify the subpopulation of Parkinson patients who will develop freezing of gait, up till 5 years in advance!
Maybe one of the best know examples of the discrimination based on eye movements, is the diagnosis of Progressive Supranuclear Palsy from idiopathic Parkinson, based on a speed reduction of vertical saccades.
In Multiple Sclerosis, existing scales can be enhanced with the analysis of eye movements, as ocular motor manifestations are highly prevalent in MS, whereas chronic manifestations may cause minimal or no symptoms. Performed in the daily practice, this can inform a treatment adaptation and improve the visual outcome.
Appropriate treatment may improve visual outcome in some of these ocular motor disorders.
Nerrant et al., in J Neuroophthalmol. 2017There are three reasons why eye tracking has not been widely implemented in the clinical practice to date.
These pains are our founders’ frustrations over 20 years of research on eye movements. We’re on a mission to answer those issues. That’s why we are developing NeuroClues®, a portable lab to help you instantaneously quantify your clinical exam, based on eye tracking.
The product is not yet available for sale and will soon undergo clinical investigations.
John R. Leigh and David S. Zee, The Neurology of Eye Movements, Fifth edition, 2015, Contemporary Neurology Series
Cécile Gallea, Benoit Wicki, Claire Ewenczyk, Sophie Rivaud-Péchoux, Lydia Yahia-Cherif, Pierre Pouget, Marie Vidailhet, Elodie Hainque, Antisaccade, a predictive marker for freezing of gait in Parkinson’s disease and gait/gaze network connectivity, Brain, Volume 144, Issue 2, February 2021, Pages 504–514, https://doi.org/10.1093/brain/awaa407
Vidailhet, M., Rivaud, S., Gouider-Khouja, N., Pillon, B., Bonnet, A.-M., Gaymard, B., Agid, Y. and Pierrot-Deseilligny, C. (1994), Eye movements in parkinsonian syndromes. Ann Neurol., 35: 420-426. https://doi.org/10.1002/ana.410350408